The WHO R&D Blueprint: 2018 review of emerging infectious diseases requiring urgent research and development efforts
Identifieur interne : 000782 ( Main/Exploration ); précédent : 000781; suivant : 000783The WHO R&D Blueprint: 2018 review of emerging infectious diseases requiring urgent research and development efforts
Auteurs : Massinissa Si Mehand [Suisse] ; Farah Al-Shorbaji [Suisse] ; Piers Millett [Royaume-Uni] ; Bernadette Murgue [Suisse]Source :
- Antiviral Research [ 0166-3542 ] ; 2018.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- diagnosis : Virus Diseases.
- prevention & control : Virus Diseases.
- statistics & numerical data : Research.
- therapy : Virus Diseases.
- Animals, Communicable Diseases, Emerging, Humans, Research Report, World Health Organization.
Abstract
The Research and Development (R&D) Blueprint is a World Health Organization initiative to reduce the time between the declaration of a public health emergency and the availability of effective diagnostic tests, vaccines, and treatments that can save lives and avert a public health crisis. The scope of the Blueprint extends to severe emerging diseases for which there are insufficient or no presently existing medical countermeasures or pipelines to produce them. In February 2018, WHO held an informal expert consultation to review and update the list of priority diseases, employing a prioritization methodology which uses the Delphi technique, questionnaires, multi-criteria decision analysis, and expert review to identify relevant diseases. The committee determined that, given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated R&D for (in no order of priority) Crimean-Congo haemorrhagic fever, Ebola virus and Marburg virus disease, Lassa fever, Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), Nipah and henipaviral diseases, Rift Valley fever and Zika virus disease. The experts also included “Disease X,” representing the awareness that a previously unknown pathogen could cause a major public health emergency. This report describes the methods and results of the 2018 prioritization review.
Url:
DOI: 10.1016/j.antiviral.2018.09.009
PubMed: 30261226
PubMed Central: 7113760
Affiliations:
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The scope of the Blueprint extends to severe emerging diseases for which there are insufficient or no presently existing medical countermeasures or pipelines to produce them. In February 2018, WHO held an informal expert consultation to review and update the list of priority diseases, employing a prioritization methodology which uses the Delphi technique, questionnaires, multi-criteria decision analysis, and expert review to identify relevant diseases. The committee determined that, given their potential to cause a public health emergency and the absence of efficacious drugs and/or vaccines, there is an urgent need for accelerated R&D for (in no order of priority) Crimean-Congo haemorrhagic fever, Ebola virus and Marburg virus disease, Lassa fever, Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), Nipah and henipaviral diseases, Rift Valley fever and Zika virus disease. 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Thokala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Royaume-Uni</li><li>Suisse</li></country><region><li>Angleterre</li><li>Oxfordshire</li></region><settlement><li>Oxford</li></settlement><orgName><li>Université d'Oxford</li></orgName></list><tree><country name="Suisse"><noRegion><name sortKey="Mehand, Massinissa Si" sort="Mehand, Massinissa Si" uniqKey="Mehand M" first="Massinissa Si" last="Mehand">Massinissa Si Mehand</name></noRegion><name sortKey="Al Shorbaji, Farah" sort="Al Shorbaji, Farah" uniqKey="Al Shorbaji F" first="Farah" last="Al-Shorbaji">Farah Al-Shorbaji</name><name sortKey="Murgue, Bernadette" sort="Murgue, Bernadette" uniqKey="Murgue B" first="Bernadette" last="Murgue">Bernadette Murgue</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Millett, Piers" sort="Millett, Piers" uniqKey="Millett P" first="Piers" last="Millett">Piers Millett</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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